Vaccine-associated polio reported in US traveler
Last Updated: 2006-02-07 15:30:36 -0400 (Reuters Health)
NEW YORK (
Reuters Health) - In a new report, researchers from the Centers
for Disease Control and Prevention in Atlanta describe what appears to be
the first case of vaccine-associated paralytic poliomyelitis in a US adult
who traveled abroad.
Although polio is rare in the US, it is endemic in other parts of the world
and for this reason, vaccination is recommended for residents traveling to
at risk areas, the researchers note in the February 2nd issue of the
Morbidity and Mortality Weekly Report.
The present case involves a young, unvaccinated woman from Arizona who
traveled to Central and South America in early 2005 as part of a
study-abroad program.
She appears to have become infected with poliovirus
through exposure to her host family's infant grandson who had recently been
given a live, attenuated oral polio vaccine (OPV).
The women experienced fever, general malaise, and progressive muscle
weakness. Her condition worsened and she was eventually admitted to the
hospital and intubated for respiratory failure. Testing revealed infection
with Sabin-strain poliovirus and although the patient eventually recovered,
she still had some weakness in the legs 60 days after disease onset.
"Healthcare providers assessing vaccine needs for unvaccinated adults
traveling to countries that use OPV should be aware of the risk that OPV
might pose to such travelers and should consider offering them polio
vaccination," the report suggests.
Mor Mortal Wkly Rep CDC Surveill Summ 2006;55:97-99.